Nandrolone Decanoate Effects and Benefits

Nandrolone decanoate effects and benefits

Nandrolone decanoate is one of the most popular and most talked about anabolic steroids in the history of bodybuilding. In this post we will examine the effects of Nandrolone decanoate on a human body, both positive and negative. This article will provide the reader with enough information so he can decide should he or shouldn’t he try to maximize his gains by using Nandrolone decanoate.

Nandrolone decanoate in bodybuilding

Nandrolone decanoate is an extremely slow acting steroid, so the results won’t be noticed quickly, but with steady supplementation, new muscle tissue will build up very nicely. It is not a surprise that this steroid is known as a very slow acting steroid; because the Decanoate ester provides Nandrolone (the hormonal compound) with a 15 day long active half-life.

Almost all users who use the supplement will need approximately good 4-6 weeks of steroid use before they are able to notice the effects, but once the effects become noticeable, you will see that they add up very quickly and you will most definitely be very pleased with that.

Because of its nature, Nandrolone decanoate is an anabolic steroid very capable of sustaining a slow, but even growth and it also provides the athletes with a couple of other benefits. Off-season training for bodybuilders can be extremely tough and demanding; pushing extremely heavy weights sometimes for two or three times a day can be very taxing for your body, and there we can see another benefit of Nandrolone decanoate. Nandrolone decanoate can provide joint relief because its hormonal part can promote the synthesis of collagen and drastically increase bone mineral content, providing the joint relief as a result of the process.

If you want to supplement with Nandrolone decanoate effectively, you have to avoid using a random dosage to make sure that you achieve maximal physical gains and stay safe while you do it. Years of experience and studies lead to the forming of a list with precise information and directions on how to stack up with Nandrolone in order to achieve your goals – increasing the mass of lean muscle in your body and reducing any potential Nandrolone side-effects. Dosage largely depends on what are you trying to achieve, so adjust your dose to your goals.

  • If you are experiencing difficulties with your joints, 100 mg per week should be enough for you to relieve the pain and get more comfortable with your workload
  • If you are trying to improve your performance and increase your muscle mass, 200 mg per week is a minimal effective dose of Nandrolone decanoate
  • If you are a recreational athlete trying to maximize your performance, maximum dosage should not exceed 400 mg per week. Doses of 500 mg or more are only recommended for elite and well experienced athletes, and even then, risks of side effects may be increased

Depending on how you look at it, Nandrolone decanoate’s weak androgenic effect, compared to Testosterone can be seen as an advantage or as a disadvantage. Testosterone is reduced at 5-A and becomes a more potent androgenic hormone (DHT), unlike Nandrolone which converts to a weak androgenic metabolite with a very little or no activity in tissues like the scalp (which reduces the risk of losing hair), prostate (decreases the risk of an enlarged prostate) and the skin (decreases the chance of acne). Although there are no steroids completely safe of these side-effects, Deca is usually considered to be one of the safest drugs in this aspect.

One attribute that is unique to Nandrolone is the ability to cushion the joints throughout heavy lifting, enabling the lifter to have more pain-free workouts. While user should never use Deca just to mask the discomfort associated with injury (because this could lead to some further internal structural damage), there are obvious advantages of finally be able to use heavy weights with no joint stress or any discomfort. The user doesn’t even have to use a large dosage of the drug to obtain this benefit, only 200-300 mg per week is more than enough for most of the individuals.

Nandrolone Decanoate Side Effects

Now, we come to the part which is probably most interesting for the majority of readers. With Nandrolone decanoate being present on the bodybuilding scene for couple of decades already, scientists and doctors were able to explore almost every aspect of its effects on human body. When used together with testosterone-based anabolic steroids, Nandrolone helps you increase the steroid intake without almost no additional side-effects.


Nandrolone decanoate can cause unwanted side effects in patients affected by severe fluid retention. Cases of edema, coupled with congestive heart failure, or without it, have been documented among Nandrolone decanoate users.


Genitourinary side effects after prolonged usage, or high dosage use of anabolics can decrease ejaculatory volume and cause oligospermia. Enlarged prostate as a side effect is possible with elderly users. That can lead to deficiencies such as urinary obstruction, painful urination and nocturia. Inadequate use among female patients can lead to acne, hirsutism, deepening voice, menstrual abnormalities and clitomegaly. Nandrolone can also increase or decrease libido.


Hepatic side effects includes wide range of hepatic abnormalities, severest one being peliosis hepatis which can present itself as a mild liver abnormality, but can result in liver failure. Other abnormalities include hepatic neoplasms or hepatocellular carcinomas induced by prolonged usage of high doses of Nandrolone decaonate. Even relatively low doses can cause cholestatic hepatitis and abnormal liver function.


Musculoskeletal side effects of Nandrolone decanoate include the blocking of epiphyseal growth center which results in the termination of bone growth. Because of this, anabolic steroids are recommended only for athletes whose skeleton is fully developed and should be avoided with prepubertal patients.


One of the positive effects of anabolic steroids on athletes is an increased number of red blood cells, but it can be followed with side effects such as prolonged prothrombin times (PT) and changes in function of clotting factors.


External administration of Nandrolone Decanoate can inhibit release and production of endogenous testosterone by inhibiting LH, the pituitary gland’s luteinizing hormone. High doses of Nandrolone can also suppress spermatogenesis by inhibiting FSH, follicles stimulating hormone. Nandrolone usage can also lead to decreased serum levels of T4, but there is no convincing clinical evidence suggesting that Nandrolone can influence thyroid function.


Metabolic side effects include changes in electrolyte balance, excretion of urinary calcium and nitrogen retention. Nandrolone decanoate can also significantly increase the concentration of LDL (low density lipoproteins ), and decrease the concentration of HDL (high density lipoproteins).


Psychiatric side effects of Nandrolone decanoate include excitation, habituation, depression, insomnia, and libido changes.


High percentage of Nandrolone users report acne as the most frequent dermatological side effect. This side effect occurs most commonly among women.

Medical Uses for Nandrolone Decanoate

As it is mentioned earlier in the article, Nandrolone decanoate was first manufactured as a treatment for certain illnesses. To this day, it was used as a treatment in various conditions, most notably osteoporosis, anemia and HIV- associated muscle wasting. It is administered as an intramuscular injection and it absorbs and travels through the bloodstream to the muscles and body tissues. Unfortunately, Nandrolone decanoate has a number of serious and life threatening side effects, so its use is mostly limited.

Anemia in Renal Insufficiency

The kidneys in normal conditions produce erythropoietin, a hormone whose function is to stimulate production of the red blood cells inside the bone marrow. People who suffer from chronic kidneys disease can often experience severe anemia, or a very low red blood cell amount, caused by insufficient production of hormone erythropoietin. Treatment with Nandrolone decanoate can help ease this condition, named anemia in renal insufficiency.

Nandrolone decanoate can increase the production of red blood cells and erythropoietin, according to the National Cancer Institute. They report that using Nandrolone decanoate is proving to be beneficial for male patients affected by anemia in renal insufficiency. However, they strongly advise against using the drug in female patients because of severe side effects. Among female patients, Nandrolone decanoate can cause some masculinizing side effects, including increased body hair, disruption of the menstrual cycle, deeper voice and male-pattern hair loss.

Treatment of anemia in renal insufficiency is the only U.S. Food and Drug Administration-approved use of Nandrolone decanoate, according to the National Library of Medicine pharmaceutical information website DailyMed.

HIV-Associated Muscle Wasting

Patients suffering from advanced HIV/AIDS can experience severe weight loss, including the loss of muscle mass. The Center for Disease Control included this condition, identified as HIV-associated muscle wasting, as an evidence of HIV disease progressing to AIDS. Doctors sometimes can prescribe Nandrolone decanoate in order to help arrest or at least partially reverse the HIV-associated wasting. Nandrolone decanoate can help patients affected by HIV-associated wasting in gaining body weight and some muscle mass. These useful effects prove to be most noticeable in patients who participate in a certain exercise program, while using Deca (Nandrolone decanoate).

Nandrolone decanoate’s therapeutic use in osteoporosis.

Nandrolone decanoate inhibits the bone resorbtion, while also increasing the formation of a new bone tissue. This can result in an increase of mineral content inside a bone, both at the proximal and the distal radius. It can even increase the bone mineral content at lumbar spine level of some patients. Nandrolone decanoate can also improve calcium balance and increase muscle mass, help with the vertebral pain and significantly increase spine mobility. Recommended dose for threating the osteoporosis in women is 50 mg per 3-4 weeks.

As we discussed today, popularity of Nandrolone decanoate (Deca) among the athletes cannot be overlooked. It has been a very significant muscle building tool for the past 50 years. While its beneficial effects on athletes and people suffering from mentioned conditions are great, the list of potential side effects must be considered too. Being so powerful, this drug has to be used with caution, preferably only by seasoned athletes. In conclusion, the rewards of using Deca can be great. It is up to us to put them on a scale and ensure we have a plan in place to manage the risks to fulfil a dream as old as the mankind is. To be big…


Leave a Reply
  1. Hola, me gustaría saber que tiempo es necesario para ver cambios significativos en mi cuerpo, ya que acabo de empezar mi primer ciclo de winstrol, deca y sustanon. Es mi segunda semana y lo estoy repartiendo de la siguiente forma : lunes y viernes sust y deca. Lunes miércoles y viernes winstrol.. Llevo sobre 18m en el gim aprox..

Leave a Reply

Your email address will not be published. Required fields are marked *